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Table 3 Thromboelastography on preoperatively , postoperative day 1, 4, and 7

From: Application of thromboelastography to evaluate the effect of different routes administration of tranexamic acid on coagulation function in total hip arthroplasty

 

Topical-TXA(n = 72)

IV-TXA (n = 68)

Control(n = 67)

 

Items

Mean ± SD

Mean ± SD

Mean ± SD

p value

R (min)

Preoperatively

6.6 ± 0.7

6.6 ± 0.8

6.8 ± 0.7

0.247

Postoperative

 Day 1

5.7 ± 0.8$*

4.9 ± 0.9#

6.0 ± 0.7

0.000

 Day 4

5.4 ± 0.6$

4.6 ± 0.8#

5.6 ± 0.6

0.000

 Day 7

6.1 ± 0.7$

5.5 ± 0.8#

6.1 ± 0.7

0.000

K (min)

Preoperatively

3.5 ± 1.0

3.5 ± 0.9

3.5 ± 0.7

0.904

Postoperative

 Day 1

2.4 ± 0.7$

2.0 ± 0.8#

2.6 ± 0.7

0.000

 Day 4

2.2 ± 0.7$

1.7 ± 0.7#

2.3 ± 0.7

0.000

 Day 7

2.7 ± 0.7$

2.0 ± 0.7#

2.8 ± 0.7

0.000

MA (mm)

Preoperatively

61.5 ± 8.4

61.3 ± 6.9

61.4 ± 9.1

0.989

Postoperative

 Day 1

64.5 ± 8.1

66.1 ± 6.8#

62.1 ± 9.2

0.017

 Day 4

67.4± ± 8.0$

70.2 ± 6.1#

66.1 ± 9.1

0.010

 Day 7

70.4 ± 4.1

70.9 ± 4.6

70.9 ± 4.1

0.695

α (°)

Preoperatively

55.4 ± 11.4

55.2 ± 12.3

55.5 ± 16.5

0.988

Postoperative

 Day 1

62.1 ± 11.4

66.3 ± 12.7

61.7 ± 16.6

0.092

 Day 4

71.5 ± 10.8$

77.6 ± 10.9#

70.6 ± 15.2

0.002

 Day 7

66.4 ± 11.6$

72.4 ± 12.5#

64.9 ± 16.6

0.004

CI

Preoperatively

0.4 ± 1.0

0.5 ± 0.9

0.4 ± 0.9

0.803

Postoperative

 Day 1

1.4 ± 1.1$

2.0 ± 0.8#

1.4 ± 0.9

0.000

 Day 4

2.3 ± 1.1$

2.9 ± 0.9#

2.3 ± 0.9

0.001

 Day 7

1.4 ± 1.2$

2.0 ± 0.8#

1.4 ± 0.9

0.000

  1. $Significant difference (p < 0.05) between topical-TXA and IV-TXA groups
  2. *Significant difference (p < 0.05) between topical-TXA and control groups
  3. #Significant difference (p < 0.05) between IV-TXA and control groups