| Topical-TXA (n = 72) | IV-TXA (n = 68) | Control (n = 67) |  |
---|---|---|---|---|
Mean ± SD | Mean ± SD | Mean ± SD | p value | |
Demographic characteristics | ||||
 Age (years) | 61.9 ± 6.1 | 62.5 ± 6.6 | 63.3 ± 6.3 | 0.407 |
 Gender male/female | 34/38 | 32/36 | 35/32 | 0.790 |
 Body mass index(kg/m2) | 22.3 ± 2.7 | 22.0 ± 2.3 | 22.2 ± 2.5 | 0.637 |
Preoperative laboratory index | ||||
 Prothrombin time (s) | 10.6 ± 0.9 | 10.6 ± 0.7 | 10.7 ± 0.73 | 0.889 |
 APTT (s) | 28.8 ± 4.2 | 29.1 ± 3.9 | 29.3 ± 3.5 | 0.735 |
 Plasma fibrinogen (g/L) | 2.9 ± 0.5 | 2.9 ± 0.6 | 2.9 ± 0.5 | 0.649 |
Postoperative complications | ||||
 Number of DVT | 1 | 0 | 0 | 0.346 |
Number of PE | 0 | 1 | 0 | 0.327 |
 Wound infection | 0 | 0 | 0 | 1.000 |
 Wound hematoma | 0 | 1 | 1 | 0.423 |
 Dislocation | 0 | 0 | 0 | 1.000 |