Table 4 OR and 95% CI for OA and IL-17F rs763780 under different genetic models
Genetic model | Ethnics | Studies | Association test | Heterogeneity | Begg’s test p value | ||
|---|---|---|---|---|---|---|---|
OR | 95% CI | p value | p value | ||||
Dominant model (TC + CC vs TT) | Total | 5 | 1.32 | 0.97–1.80 | 0.073 | 0.017 | 0.221 |
Asian | 3 | 1.12 | 0.78–1.60 | 0.533 | 0.029 | ||
Caucasian | 2 | 1.88 | 1.29–2.75 | 0.001 | 0.582 | ||
Allele model (C vs T) | Total | 6 | 1.35 | 1.08–1.68 | 0.008 | 0.061 | 0.452 |
Asian | 3 | 1.18 | 0.86–1.62 | 0.302 | 0.032 | ||
Caucasian | 3 | 1.66 | 1.25–2.22 | 0.001 | 0.703 | ||
Recessive model (CC vs TT + TC) | Total | 5 | 2.28 | 1.39–3.76 | 0.001 | 0.953 | 0.086 |
Asian | 3 | 2.41 | 1.42–4.10 | 0.001 | 0.889 | ||
Caucasian | 2 | 1.41 | 0.31–3.76 | 0.655 | 0.969 | ||