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Table 4 Micro-CT based histomorphometry of femoral fracture at 8 weeks

From: Enhancement of the effects of intermittent parathyroid hormone (1-34) by bone morphogenetic protein in a rat femoral open fracture model

Treatment group

 

No. studied micro-CT

Tb.Th (mm)

Tb.N (1/mm)

Tb.Sp (mm)

Group I

Carrier alone

6

0.63 ± 0.09

0.95 ± 0.13

1.01 ± 0.18

Group II

1 μg rhBMP-2

6

0.67 ± 0.09

0.93 ± 0.10

0.91 ± 0.18

Group III

Carrier + PTH

6

0.77 ± 0.11

0.88 ± 0.10

0.85 ± 0.12

Group IV

1 μg rhBMP-2 + PTH

6

0.71 ± 0.05

0.94 ± 0.03

0.97 ± 0.23

Group V

10 μg rhBMP-2

6

0.60 ± 0.08

1.03 ± 0.04

0.76 ± 0.05

Group VI

10 μg rhBMP-2 + PTH

6

0.70 ± 0.06

1.01 ± 0.08

0.85 ± 0.06

  1. Tb.Th trabecular thickness, Tb.N trabecular number, Tb.Sp trabecular separation