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Table 3 Micro-CT based histomorphometry of femoral fracture at 8 weeks

From: Enhancement of the effects of intermittent parathyroid hormone (1-34) by bone morphogenetic protein in a rat femoral open fracture model

Treatment group No. studied micro-CTTV (mm3)BV (mm3)BV/TV (%)
Group ICarrier alone6607.83 ± 214.20351.64 ± 111.8158.26 ± 1.86
Group II1 μg rhBMP-26528.48 ± 45.28325.40 ± 24.1061.68 ± 3.05
Group IIICarrier + PTH6473.23 ± 44.46316.85 ± 18.6567.23 ± 4.29
Group IV1 μg rhBMP-2 + PTH6483.73 ± 43.25323.01 ± 36.7166.74 ± 4.26
Group V10 μg rhBMP-26480.45 ± 66.31295.07 ± 34.6161.88 ± 3.16*
Group VI10 μg rhBMP-2 + PTH6440.52 ± 70.41313.43 ± 54.4671.14 ± 3.89*
  1. TV tissue volume, BV bone volume, BV/TV percent bone volume
  2. *p < 0.05 (vs group 1)