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Table 2 Univariate and multivariate analyses of risk factors for aseptic loosening

From: Establishment and validation of a nomogram model for aseptic loosening after tumor prosthetic replacement around the knee: a retrospective analysis

Variables

Number of cases

Survival rate (%)

Mean survival time (months)

p value

Multivariate analysis

5 years

10 years

  

HR

95% CI

p value

Sex

 Female

61

89.6

85.8

163.1

    

 Male

116

96.9

84.6

149.9

0.496

  

NI

Age

 > 30 years

95

92.8

83.6

153.4

    

 ≤ 30 years

82

92.6

86.4

161.0

0.627

  

NI

Extra-cortical grafting

 Yes

17

86.2

78.3

167.0

    

 No

160

93.5

85.8

155.2

0.826

  

NI

Type of prosthesis

 Custom

103

93.4

85.5

158.8

    

 Modular

74

88.4

NA

84.9

0.675

  

NI

Diameter of prosthetic stem

 ≥ 13 mm

72

88.8

74.5

137.7

    

 < 13 mm

74

92.6

88.9

154.0

0.611

  

NI

Material for prosthetic stem

 CoCrMo

56

92.9

NA

77.3

    

 Titanium

117

92.0

84.3

157.0

0.698

  

NI

Type of tumor

 Benign

61

100

84.6

152.5

    

 Malignant

116

88.4

86.6

171.5

0.432

  

NI

Intensity of activity

 High

46

86.7

NA

96.3

    

 Low

94

90.3

63.7

108.9

0.347

  

NI

BMI

 ≥ 25

105

89.9

72.5

116.5

    

 < 25

50

93.0

88.6

121.3

0.823

  

NI

Tumor site

 Distal femur

119

90.9

82.5

151.8

 

3.99

  

 Proximal tibia

58

95.4

89.0

170.8

0.150

1

(1.21, 13.16)

0.023

Length of prosthetic stem

 ≥ 14 cm

73

94.1

88.8

143.5

 

1

  

 < 14 cm

75

82.5

52.9

121.4

0.059

2.84

(1.13, 7.12)

0.026

Length of bone resection

 ≥ 14 cm

82

88.0

79.6

142.7

    

 < 14 cm

89

95.6

88.3

166.8

0.046

  

0.382

Prosthetic motion mode

 Fixed hinge

19

77.8

66.7

113.6

 

4.11

  

 Rotating hinge

158

94.6

88.0

170.0

0.001

1

(1.74, 9.70)

0.001

  1. NI not included, NA not available