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Table 2 Effects of pain, anxiety, and depression on knee function

From: Depression negatively affects patient-reported knee functional outcome after intraarticular hyaluronic acid injection among geriatric patients with knee osteoarthritis

 

B (SE)

IKDC

WOMAC_P

WOMAC_S

WOMAC_F

WOMAC_T

VAS_L

− 1.419

(0.280)***

0.280

(0.107)**

0.151

(0.053)**

0.516

(0.316)

0.977

(0.421)*

VAS_R

− 1.337

(0.313)***

0.362

(0.118)**

0.055

(0.059)

1.158

(0.353)**

1.515

(0.470)**

STAIa

− 0.077

(0.072)

0.056

(0.028)*

0.003

(0.014)

0.093

(0.081)

0.148

(0.108)

Geriatric depression scale

− 1.064

(0.259)***

0.185

(0.098)#

0.054

(0.049)

1.348

(0.292)***

1.595

(0.389)***

2 months (Ref: baseline)

− 0.678

(0.867)

− 0.262

(0.347)

− 0.215

(0.175)

− 1.250

(0.971)

− 1.766

(1.306)

4 months (Ref: baseline)

− 0.314

(1.046)

− 0.007

(0.405)

− 0.129

(0.202)

− 1.015

(1.178)

− 1.171

(1.573)

6 months (Ref: baseline)

− 0.882

(1.156)

0.042

(0.433)

0.040

(0.215)

− 0.740

(1.311)

− 0.692

(1.736)

Gender (Ref: female)

3.878

(1.783)

0.631

(0.567)

− 0.397

(0.272)

− 1.617

(2.101)

− 1.417

(2.656)

Married (Ref: single)

− 14.214

(5.380)

1.513

(1.749)

0.914

(0.844)

2.258

(6.310)

4.633

(8.019)

Widowed (Ref: single)

− 17.211

(5.679)

2.404

(1.846)

0.818

(0.891)

3.957

(6.661)

7.133

(8.465)

Hypertension (Ref: yes)

1.085

(1.618)

− 0.322

(0.514)

0.188

(0.247)

− 0.990

(1.907)

− 1.184

(2.410)

DM (Ref: yes)

1.650

(1.954)

− 0.125

(0.617)

0.382

(0.296)

− 3.531

(2.305)

− 3.294

(2.908)

Heart disease (Ref: yes)

1.784

(2.007)

− 1.326

(0.640)

− 0.764

(0.308)

− 0.965

(2.363)

− 3.044

(2.989)

Depression (Ref: yes)

− 8.059

(6.055)

3.732

(1.961)

0.445

(0.946)

7.895

(7.107)

12.162

(9.024)

Cancer (Ref: yes)

3.241

(5.736)

− 2.932

(1.818)

0.536

(0.873)

− 5.338

(6.762)

− 7.969

(8.539)

Age

− 0.317

(0.117)**

− 0.023

(0.037)

0.025

(0.018)

0.393

(0.137)**

0.396

(0.174)*

  1. VAS_L, Visual Analogue Scale on left knee pain; VAS_R, Visual Analogue Scale on right knee pain; DM, diabetes mellitus; IKDC, The International Knee Documentation Committee Questionnaire; WOMAC, Western Ontario and McMaster University Osteoarthritis Index
  2. #p = 0.061; *p < 0.05; **p < 0.01; ***p < 0.001
  3. aState and Trait Anxiety Inventory; only the state scale was used