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Table 4 Diagnostic values of other serum or synovial fluid biomarkers for PJI

From: Reliability of synovial fluid alpha-defensin and leukocyte esterase in diagnosing periprosthetic joint infection (PJI): a systematic review and meta-analysis

BiomarkerSensitivity (95% CI)Specificity (95% CI)
Erythrocyte sedimentation rate (ESR)86% (82.5–89%)72.3% (70.4–74.2%)
Serum C-reactive protein (CRP)86.9% (83.5–89.9%)78.6% (86.9–80.3%)
Synovial fluid procalcitonin (PCT)53% (24–80%)92% (45–99%)
Synovial fluid CRP92% (86–96%)90% (87–93%)
Synovial fluid interleukin-6 (IL-6)72% (63–80%)91% (82–96%)