Table 3 Pooled diagnostic parameters of ELISA and lateral flow test strip for α-defensin
ELISA | Lateral flow test strip | |
|---|---|---|
Number of studies | 4 | 12 |
Sensitivity (95% CI) | 92% (86–96%) | 85% (80–89%) |
Specificity (95% CI) | 99% (98–100%) | 96% (94–97%) |
Positive likelihood ratio (95% CI) | 91.18 (29.53–281.49) | 14.91 (8.51–26.15) |
Negative likelihood ratio (95% CI) | 0.10 (0.06–0.18) | 0.19 (0.11–0.34) |
Diagnostic odds ratio (95% CI) | 1095.49 (283.68–4230.45) | 97.55 (46.69–203.83) |
AUC | 0.9990 | 0.9590 |