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Table 4 Levels of uCTX-II, uC2C, uPYD, and uHelix-II in the different KBD grade groups

From: The urinary levels of CTX-II, C2C, PYD, and Helix-II increased among adults with KBD: a cross-sectional study

Markers

IC (grade 0 KBD)

Grade I KBD

Grade II KBD

H

P

Median

P25, P75

Median

P25, P75

Median

P25, P75

uCTX-II (ng/mmol.cre)

27.48

23.20, 33.80

40.15

29.63, 56.81

56.59

37.05, 77.76

42.707

< 0.001c

uC2C (ng/mmol.cre)

1.67

1.27, 2.02

1.99

1.39, 3.06

3.01

1.64, 4.45

17.808

< 0.001c

uPYD (nmol/mmol.cre)

24.93

20.83, 29.88

30.54

19.56, 43.51

47.61

28.14, 73.91

13.474

0.001c

uHelix-II (nmol/mmol.cre)

0.35

0.27, 0.50

0.44

0.31, 0.70

0.67

0.30, 1.29

9.760

0.008c

  1. IC internal control, KBD Kashin-Beck disease
  2. cKruskal-Wallis H test