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Table 3 Genotype association between SNP in COMP (HpyCH4IV_rs34467947) gene and knee osteoarthritis (KOA)

From: Identifying the role of ASPN and COMP genes in knee osteoarthritis development

  

All subjects

Women

Men

Control (%)

Case (%)

OR (95% CI), p value

Control (%), 276

Case (%), 295

OR (95% CI), p value

Control (%), 224

Case (%), 205

OR (95% CI), p value

Genotype

HpyCH4IV-rs34467947

         
 

CC

467 (93.4)

458 (91.6)

1.00 (ref)

259 (93.84)

272 (92.20)

1.00 (ref)

208 (92.85)

186 (90.73)

1.00 (ref)

CT

29 (5.8)

35 (7.0)

1.23 (0.74–2.04), 0.423

14 (5.07)

18 (6.10)

1.22 (0.59–2.51), 0.580

15 (6.69)

17 (8.29)

1.26 (0.61–2.60), 0.519

TT

4 (0.8)

7 (1.4)

1.78 (0.51–6.13), 0.351

3 (1.08)

5 (1.69)

1.58 (0.37–6.70), 0.526

1 (0.04)

2 (0.9)

2.23 (0.20–24.86), 0.501

Allele

C

963 (96.3)

951 (95.1)

1.00 (ref)

532 (96.37)

562 (95.25)

1.00 (ref)

431 (96.20)

389 (94.87)

1.00 (ref)

T

37 (3.7)

49 (4.9)

1.34 (0.86–2.07), 0.185

20 (3.62)

28 (4.74)

1.32 (0.73–2.38), 0.344

17 (3.79)

21 (5.12)

1.36 (0.71–2.63), 0.345

  1. OR odds ratio, 95% CI 95% confidence interval, ref reference category