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Table 1 List of potential outcomes

From: How to evaluate the clinical outcome of joint-preserving treatment for osteonecrosis of the femoral head: development of a core outcome set

Categories Outcomes
Common signs and symptoms Harris Hip Score (HHS)
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Visual analogue scale (VAS)
Charnley score
Merle D’Aubigne score
Japanese Orthopedic Association Score (JOA)
Method used to determine the percentage of adult ONFH
Syndrome integral to TCM
Clinical effective rate
ROM of flexion
Walking distance
Degree of claudication
Quality of life MOS Short-Form Health Survey (SF-36)
12-item Short-Form Health Survey (SF-12)
Quality of Life Brief Scale (QOL-BREF)
EORTC-30 Scale
Barthel index
Long-term outcomes Femoral head survival time
Hip joint arthroplasty rate
Femoral head collapse rate
Femoral head survival rate
Radiological evaluation Degree of X-ray change
Degree of computed tomography (CT) change
Degree of bone marrow edema
Percentage of empty lacunae
Sample line of magnetic resonance imaging (MRI)
Necrotic bone resorption rate
New bone repair rate
Bone mineral density
Blood biochemistry Erythrocyte sedimentation rate (ESR)
Lipid indexes
Bone Gla protein (BGP)
Endothelin (ET)
Bone morphogenetic protein 2 (BMP2)
Osteoblasts (OB)
Osteoclasts (OC)
Osteoprotegerin (OPG)
Alkaline phosphatase (ALP)
C-reactive protein (CRP)
Indexes of safety Adverse effect rate
Adverse events
Detection of blood biochemical indexes