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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: A placebo-controlled study comparing the efficacy of intra-articular injections of hyaluronic acid and a novel hyaluronic acid-platelet-rich plasma conjugate in a canine model of osteoarthritis

Fig. 4

Macroscopic evaluation of the synovium and articular cartilage from all groups. Macroscopic lesions of the synovium (a) and articular cartilage (c) in the affected knees of all experimental groups. Comparison of the OARSI scores of the gross lesion in the affected synovium and articular cartilage (b, d). Proliferation and thickening with increased vascularity of the synovium were identified from the control and the HA group (a, white arrows). Fibrillation and roughen articular surface were observed in the weight-bearing areas of the femoral condyle and the tibial plateau (c, white arrowheads). *Significant difference (p < 0.05) between the treatment groups and the control group. OARSI scores of the synovium (p > 0.05) and articular cartilage (p > 0.05) were not significantly different when comparing between HA and HA-PRP group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X