Skip to main content


Table 4 Demographic characteristics of included participants

From: Gout is not associated with the risk of fracture: a meta-analysis

Author Year Female, n (%) Mean age, years (SD) Mean duration of follow-up, years Comorbidities
Urate-lowering group Control group Urate-lowering group Control group Urate-lowering group Control group
Dennison, et al. [26] 2015 27,967 (33) 27,967 (33) 63 (15.1) 63 (15.1) 7 7 Allopurinol use, prior fracture, known comorbidity, drug history
Tzeng, et al. [23] 2016 Not mentioned Not mentioned Not mentioned Not mentioned 11 11 Age, sex, ALD, CAD, COPD, DM, ESRD, hypertension, osteoporosis, Parkinson disease, stroke, and each drug
Basu, et al. [28] 2016 487 (43.7) 9684 (60.0) 73.2 (8.4) 73.4 (9.0) 12 12 Age, sex, creatinine, albumin, hemoglobin, diagnosis of diabetes mellitus, previous admission with ischemic heart disease, stroke, chronic heart failure, COPD, bisphosphonate prescription, vitamin D and calcium prescription, any exposure to allopurinol prior to the index date, and provision of a package of social care
Sultan, et al. [1] 2018 1925 (28.5) 6443 (26.1) 64.9 (12.0) 63.0 (12.5) 10.8 10.8 Age, alcohol consumption, smoking status, BMI, Charlson index, opioids, fall, glucocorticoids, nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, proton pump inhibitors, antidiabetic and antihypertensive agents, and selective serotonin reuptake inhibitors
  1. ALD alcohol-related disorder, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, DM diabetes mellitus, ESRD end-stage renal disease