Enhancement of cartilage repair through the addition of growth plate chondrocytes in an immature skeleton animal model

Table 4 Microscopic evaluation of cartilage according to ICRS

	1L	2P	3L	5P	6P	7P	8P	9P	10P	1P	2L	3P	5L	6L	7L	8L	9L	10L
Tissue morphology	68	65	62	71	50.5	40	52	52	60	88	88	84	82.5	45	39	55	80	65
Matrix staining	79	53	55	75.5	32	59	34	47	25	90	89	90	94	30	59	61	68	45
Cell morphology	80	55	80	70	26.5	75	36	54	52	84	79	86.5	91.5	44	56	61.5	62	57
Chondrocyte clustering	40	48	55	65	56	62	60	55	65	45	50	65	55	52	55	52	55	56
Surface architecture	90	79	78	51.5	79.5	96	79	89	79	96	89	88	81	81	82	90	96	90
Basal integration.	90	88	89	75	77.5	85	82	73	82	95	95	94	85	81	84	92	91	85
Formation of tidemark	25	24	30	36	18	22	21	25	21	35	44	42	44	20	34	30	44	38
Subchondral bone abnormalities	84	55	89	48	47	70	90	65	88	93.5	95	95.5	89	76.5	65	91.5	95	96
Inflammation	100	100	100	62.5	82	100	82	75	97	100	100	100	77	80.5	92	89	95	100
Abnormal calcification/ossification	100	100	100	87	100	100	100	100	100	100	100	100	100	100	100	100	100	100
Vascularization	86	20	95	70	52	50	42	45	70	100	92.5	96	94	50	48	55	95	75
Superficial assessment	81	60	72.5	70	45	72	62	62	80	92	91.5	91.5	91.5	38	67	60	72	75
Mid/deep zone assessment	80	62	75	75.5	61	75	71	66	76	89	92	89	82	75	50	83	84	85
Overall assessment	84	65	75	64	61	71	69	74	71	90	93	91.5	80	68	60	78	80	76
Scaffold with cells—CELLS										+	+	+	+	+	+	+	+	+
Scaffold without cells—CTRL	+	+	+	+	+	+	+	+	+

ISSN: 1749-799X