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Table 7 Literature review of bone graft substitute

From: Early postoperative compilations of bone filling in curettage defects

Author Year Cases Fracture Infection Cellulitis PE Parastesia/neuralpraxia Other Rate (%) Type
Takeuchi et al. [41] 2018 26 1 1 0 0 0 0 7.69 Calcium phosphate
Rajeh et al. [42] 2017 8 0 0 0 0 0 0 0.00 Calcium phosphate
Rosario et al. [43] 2017 12 0 0 0 0 0 0 0.00 Calcium phosphate
Sakamoto et al. [44] 2017 4 0 0 0 0 0 0 0.00 Calcium phosphate
Guida et al. [7] 2016 116 0 0 3 0 0 0 2.59 Calcium phosphate
Damron et al. [45] 2013 55 0 0 0 0 0 0 0.00 Calcium phosphate
Gentile et al. [46] 2013 16 0 0 0 0 0 0 0.00 Calcium phosphate
Seto et al. [47] 2013 34 0 0 0 0 0 0 0.00 Calcium phosphate
Reppenhagen et al. [48] 2012 51 0 0 1 0 1 1a 5.88 Calcium phosphate
Van Hoff et al. [49] 2012 29 0 0 0 0 0 1b 3.45 Calcium phosphate
El-Adl et al. [50] 2009 34 0 2 1 0 0 0 8.82 Calcium phosphate
Hirata et al. [51] 2006 53 0 0 0 0 0 0 0.00 Calcium phosphate
Matsumine et al. [52] 2006 56 1 0 1 0 0 0 3.57 Calcium phosphate
Ogose et al.[53] 2005 53 4 0 0 0 0 0 7.55 Calcium phosphate
Yamamoto et al. [54] 2000 75 2 0 0 0 0 0 2.67 Calcium phosphate
Nicholas et al. [55] 1994 18 1 0 1 0 0 0 11.11 Calcium phosphate
Capanna et al. [56] 1991 21 0 1 0 0 0 0 4.76 Calcium phosphate
Andreacchio et al. [8] 2018 9 0 0 0 0 0 0 0.00 Calcium sulfate
Muramatsu et al. [57] 2014 5 0 0 0 0 0 1c 20.00 Calcium sulfate
Yang et al. (32) 2014 50 0 0 2 0 0 0 4.00 Calcium sulfate
Kim et al. [5] 2011 28 2 0 0 0 0 0 7.14 Calcium sulfate
Hou et al. [58] 2010 31 1 0 0 0 0 0 3.23 Calcium sulfate
Kelly and Wilkins [59] 2004 15 1 1 1 0 0 0 20.00 Calcium sulfate
Nakamura et al. [60] 2016 33 0 1 1 0 0 0 6.06 Calcium sulfate + tricalcium phosphate
Auston et al. [61] 2015 87 1 0 0 0 0 0 1.15 Calcium sulfate + tricalcium phosphate
Friesenbichler et al. [62] 2014 31 0 0 0 0 0 5d 16.13 Calcium sulfate + tricalcium phosphate
Total   950 14 6 11 0 1 8 4.21  
    1.47% 0.63% 1.16% 0.00% 0.11% 0.84%   
  1. a1 case of CPRS
  2. b1 case of avascular necrosis
  3. c1 case of CPRS
  4. d3 cases of aseptic skin inflammation, 2 cases of soft tissue cystic inflammation