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Table 3 The GRADE evidence quality

From: Cementless versus cemented total knee arthroplasty in young patients: a meta-analysis of randomized controlled trials

Quality assessment No. of patients Effect Quality Importance
No. of studies Design Limitations Inconsistency Indirectness Imprecision Cementless groups Cemented groups
Functional recovery
 6 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 229 255 WMD − 0.239; 95% CI − 2.154 to − 1.676 High Critical
Range of motion
 4 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 201 199 WMD − 5.284; 95% CI − 9.430 to − 1.139 High Critical
Pain score
 4 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 140 141 WMD − 3.029; 95% CI − 5.119 to − 0.939 High Critical
Radiological outcomes
 6 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 229 255 RD 0.058; 95% CI 0.004 to 0.111 High Critical
Aseptic loosening
 5 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 194 221 RD − 0.001; 95% CI − 0.030 to 0.028 High Critical
Postoperative complications
 6 RCT No serious limitations No serious inconsistency No serious indirectness No serious limitations 229 255 RD 0.007; 95% CI − 0.019 to 0.033 High Critical