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Table 1 Performance of serum tests for diagnosing PJI

From: Comparison of D-dimer with CRP and ESR for diagnosis of periprosthetic joint infection

 

D-dimer

CRP

ESR

True positive

21

22

19

False positive

11

19

5

False negative

5

4

7

True negative

43

35

49

Sensitivity (95%CI)

80.77% (65.62–95.92%)

84.61% (70.74–98.48%)

73.08% (56.03–90.13%)

Specificity (95%CI)

79.63% (68.89 90.37%)

64.81% (52.41–74.81%)

90.47% (82.74–98.47%)

AUC (95%CI)

0.890 (0.814–0.966)

0.831 (0.737–0.926)

0.838 (0.732–0.944)

  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio