|
Variable
|
rs11564299 (case/control)
|
AG vs. AA
|
GG vs. AA
|
GG vs. AA+AG
|
GG+AG vs. AA
|
|---|
| |
AA
|
AG
|
GG
| | | | |
|---|
|
Sex
|
|
Male
|
44/50
|
19/24
|
6/24
|
0.90 (0.44–1.86); 0.775
|
6.82 (0.79–58.80); 0.081
|
7.04 (0.83–60.06); 0.074
|
1.14 (0.57–2.26); 0.715
|
|
Female
|
168/246
|
91/90
|
17/90
|
1.47 (1.04–2.09); 0.031
|
2.25 (1.03-4.92); 0.043
|
2.00 (0.92–4.34); 0.080
|
1.56 (1.11–2.18); 0.010
|
|
Smoking
|
|
Yes
|
135/213
|
79/73
|
12/7
|
1.71 (1.16–2.51); 0.006
|
2.71 (1.04–7.04); 0.042
|
2.29 (0.89–5.92); 0.087
|
1.80 (1.24–2.60); 0.002
|
|
No
|
78/83
|
31/41
|
11/5
|
0.81 (0.46–1.41); 0.446
|
2.34 (0.78–7.04); 0.130
|
2.50 (0.84–7.43); 0.099
|
0.97 (0.58–1.63); 0.914
|
|
Alcohol
|
|
Yes
|
129/198
|
71/80
|
16/6
|
1.36 (0.92–2.01); 0.119
|
4.09 (1.56–10.73); 0.004
|
3.71 (1.43–9.63); 0.007
|
1.55 (1.07–2.25); 0.020
|
|
No
|
84/98
|
39/34
|
7/6
|
1.34 (0.78–2.31); 0.294
|
1.36 (0.44–4.21); 0.592
|
1.25 (0.41–3.83); 0.694
|
1.34 (0.80–2.24); 0.263
|
|
Age (years)
|
|
< 60
|
77/109
|
47/38
|
6/4
|
1.75 (1.04–2.94); 0.034
|
2.12 (0.58–7.78); 0.256
|
1.78 (0.49–6.44); 0.381
|
1.79 (1.08–2.94); 0.023
|
|
≥ 60
|
136/187
|
63/75
|
17/8
|
1.14 (0.76–1.70); 0.522
|
2.92 (1.23–6.97); 0.016
|
2.81 (1.19–6.64); 0.019
|
1.31 (0.90–1.91); 0.162
|
|
BMI
|
|
< 25
|
75/94
|
43/44
|
6/4
|
1.23 (0.73–2.06); 0.443
|
1.88 (0.51–6.91); 0.342
|
1.75 (0.48–6.37); 0.392
|
1.28 (0.78–2.11); 0.335
|
|
≥ 25
|
138/202
|
67/70
|
17/8
|
1.40 (0.94–2.09); 0.098
|
3.11 (1.31–7.41); 0.010
|
2.82 (1.19–6.66); 0.018
|
1.58 (1.08–2.30); 0.018
|
- Values in italics are statistically significant (P < 0.05)
