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Table 3 Stratified analyses between rs11564299 polymorphisms and the risk of osteoarthritis

From: CDH2 gene rs11564299 polymorphism is a risk factor for knee osteoarthritis in a Chinese population: a case–control study

Variable rs11564299 (case/control) AG vs. AA GG vs. AA GG vs. AA+AG GG+AG vs. AA
  AA AG GG     
Sex
 Male 44/50 19/24 6/24 0.90 (0.44–1.86); 0.775 6.82 (0.79–58.80); 0.081 7.04 (0.83–60.06); 0.074 1.14 (0.57–2.26); 0.715
 Female 168/246 91/90 17/90 1.47 (1.04–2.09); 0.031 2.25 (1.03-4.92); 0.043 2.00 (0.92–4.34); 0.080 1.56 (1.11–2.18); 0.010
Smoking
 Yes 135/213 79/73 12/7 1.71 (1.16–2.51); 0.006 2.71 (1.04–7.04); 0.042 2.29 (0.89–5.92); 0.087 1.80 (1.24–2.60); 0.002
 No 78/83 31/41 11/5 0.81 (0.46–1.41); 0.446 2.34 (0.78–7.04); 0.130 2.50 (0.84–7.43); 0.099 0.97 (0.58–1.63); 0.914
Alcohol
 Yes 129/198 71/80 16/6 1.36 (0.92–2.01); 0.119 4.09 (1.56–10.73); 0.004 3.71 (1.43–9.63); 0.007 1.55 (1.07–2.25); 0.020
 No 84/98 39/34 7/6 1.34 (0.78–2.31); 0.294 1.36 (0.44–4.21); 0.592 1.25 (0.41–3.83); 0.694 1.34 (0.80–2.24); 0.263
Age (years)
 < 60 77/109 47/38 6/4 1.75 (1.04–2.94); 0.034 2.12 (0.58–7.78); 0.256 1.78 (0.49–6.44); 0.381 1.79 (1.08–2.94); 0.023
 ≥ 60 136/187 63/75 17/8 1.14 (0.76–1.70); 0.522 2.92 (1.23–6.97); 0.016 2.81 (1.19–6.64); 0.019 1.31 (0.90–1.91); 0.162
BMI
 < 25 75/94 43/44 6/4 1.23 (0.73–2.06); 0.443 1.88 (0.51–6.91); 0.342 1.75 (0.48–6.37); 0.392 1.28 (0.78–2.11); 0.335
 ≥ 25 138/202 67/70 17/8 1.40 (0.94–2.09); 0.098 3.11 (1.31–7.41); 0.010 2.82 (1.19–6.66); 0.018 1.58 (1.08–2.30); 0.018
  1. Values in italics are statistically significant (P < 0.05)