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Table 4 Radiological and clinical results comparing preoperative and postoperative outcomes in OWHTO or CWHTO group

From: Radiographic changes and clinical outcomes after open and closed wedge high tibial osteotomy: a systematic review and meta-analysis

Categories and comparison

Studies

Mean difference

p value

Heterogeneity

Mean

(95% CI)

I2 (%)

p value

Preoperative VS postoperative results in CWHTO

Radiological outcomes RCT

 HKA

10, 24,26,27,30

− 3.17

(− 3.74 to − 2.60)

0.001

79

0.001

 MAD

26

− 2.31

(− 2.92 to − 1.70)

0.001

NA

NA

 MMPTA

26

− 2.90

(− 3.58 to − 2.23)

0.001

NA

NA

 PTSA (AX)

24,26

0.72

(0.35 to 1.08)

0.001

4.8

0.31

 CDI

27,30

− 0.11

(− 0.50 to 0.29)

0.59

0

0.59

 ISI

26,31

− 0.10

(− 0.46 to 0.26)

0.58

0

0.84

 BPI

31

− 0.18

(− 0.75 to 0.39)

0.53

NA

NA

Radiological outcomes nRCT

 HKA

17,21,33,36,39,41

− 2.75

(− 3.77 to − 1.73)

0.001

95

0.001

 MAD

23

− 6.20

(− 7.46 to -4.95)

0.001

NA

NA

 MMPTA

23

− 1.54

(− 2.13 to − 0.95)

0.001

NA

NA

 PTSA (AX)

16,21,23

0.35

(0.13 to 0.58)

0.015

28.8

0.24

 PTSA (PC)

12,18,22,38

0.56

(0.20 to 0.92)

0.003

68.8

0.003

 CDI

15,38,42

− 0.13

(− 0.33 to 0.07)

0.19

48.9

0.19

 ISI

22,38

− 0.03

(− 0.33 to 0.28)

0.69

0

0.87

 BPI

22,36,38

0.06

(− 0.22 to 0.34)

0.69

74.4

0.05

 AFTA

22,33,40

− 3.19

(− 3.54 to − 2.69)

0.001

0

0.73

Clinical outcomes RCT

 VAS

10,13,24,27,30,31

1.66

(1.05 to 2.27)

0.001

84.7

0.001

 ROM

24

− 0.11

(− 0.61 to 0.40)

0.68

NA

NA

 HSS

2,10,11

− 1.06

(− 1.34 to − 0.79)

0.001

84

0.002

 KSS

24

− 1.61

(− 2.19 to − 1.02)

0.001

NA

NA

 WOMAC

27,30

1.65

(1.19 to 2.11)

0.001

54

0.14

Clinical outcomes nRCT

 Lysholm

13

− 1.40

(− 2.16 to − 0.69)

0.001

NA

NA

 ROM

21

− 0.15

(− 0.54 to 0.24)

0.45

NA

NA

 HSS

21,23

− 0.09

(− 0.38 to 0.20)

0.55

0

0.45

 KSS

23,36

− 1.68

(− 2.72 to − 0.63)

0.002

90.6

0.52

Preoperative VS postoperative results in OWHTO

Radiological outcomes RCT

 HKA

10, 24,26,27,30

− 2.78

(− 3.12 to − 2.45)

0.001

91.4

0.001

 MAD

26

− 1.95

(− 2.52 to − 1.38)

0.001

NA

NA

 MMPTA

26

− 2.76

(− 3.42 to − 2.10)

0.001

NA

NA

 PTSA (AX)

24,26

− 0.59

(− 0.94 to − 0.23)

0.001

0

0.68

 CDI

27,30

0.65

(0.25 to 1.06)

0.002

0

0.45

 ISI

26,31

0.28

(0.08 to 0.64)

0.04

0

0.34

 BPI

31

0.58

(0.03 to 1.14)

0.04

NA

NA

Radiological outcomes nRCT

 HKA

17,21,33,36,39,41

− 2.84

(− 3.14 to − 2.55)

0.001

93.3

0.001

 MAD

23

− 7.03

(− 7.83 to − 6.24)

0.001

NA

NA

 MMPTA

23

− 1.98

(− 2.35 to − 1.62)

0.001

NA

NA

 PTSA (AX)

16,21,23

− 0.71

(− 1.04 to − 0.37)

0.001

69.5

0.02

 PTSA (PC)

12,18,22,38

− 0.24

(− 0.39 to − 0.09)

0.002

42.7

0.17

 CDI

15,38,42

0.56

(0.40 to 0.72)

0.001

39.9

0.001

 ISI

22,38

0.18

(− 0.14 to 0.50)

0.26

25.8

0.25

 BPI

21,36,38

0.92

(0.63 to 1.21)

0.001

29.6

0.23

 AFTA

22,33,40

− 3.04

(− 3.41 to − 2.67)

0.001

39

0.19

Clinical outcomes RCT

 VAS

10,13,24,27,30,31

1.65

(1.03 to 2.26)

0.001

84.6

0.001

 ROM

24

− 0.35

(− 0.86 to 0.17)

0.18

NA

NA

 HSS

10,24,31

− 1.52

(− 2.16 to − 0.88)

0.009

89.6

0.001

 KSS

24

− 2.14

(− 2.78 to − 1.50)

0.001

NA

NA

 WOMAC

27,30

1.22

(0.69 to 1.55)

0.001

80.5

0.02

Clinical outcomes nRCT

 Lysholm

13

− 1.53

(− 2.19 to − 0.87)

0.001

NA

NA

 ROM

43

− 0.16

(− 0.51 to 0.28)

0.57

NA

NA

 HSS

21,23

− 1.72

(− 2.38 to − 1.06)

0.001

80

0.001

 KSS

23,31

− 1.52

(− 2.52 to − 0.52)

0.003

85.1

0.01

  1. AX Anatomical axia, PC posterior cortex, RCT randomized controlled trial, nRCT non-randomized controlled trial, NA not available, ROM range of motion, HSS Hospital for Special Surgery Knee Score, KSS American Knee Society Score, VAS Visual Analog Scale Pain Score, WOMAC the total of Western Ontario and McMaster University Osteoarthritis Index, AFTA anatomical femorotibial angle, HKA hip-knee-ankle angle, MAD mechanical axis deviation, MMPTA mechanical medial proximal tibia angle, PTSA posterior tibial slope angle, CDI Caton-Deschamps Index, ISI Insall-Salvati Index, BPI Blackburne-Peel index