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Table 3 Radiological and clinical results of the preoperative comparison and postoperative comparison between OWHTO and CWHTO

From: Radiographic changes and clinical outcomes after open and closed wedge high tibial osteotomy: a systematic review and meta-analysis

Categories and comparison

Studies

Mean difference

P value

Heterogeneity

Mean

(95% CI)

I2 (%)

p value

CWHTO VS OWHTO in preoperative outcomes

Radiological outcomes RCT

 HKA

10, 24,26,27,30

0.11

(− 0.11 to 0.33)

0.33

0

0.792

 MAD

26

0

(− 0.47 to 0.47)

0.90

NA

NA

 MMPTA

26

0

(− 0.46 to 0.46)

0.95

NA

NA

 PTSA (AX)

24,26

− 0.14

(− 0.48 to 0.21)

0.38

0

0.39

 CDI

27,30

0.01

(− 0.39 to 0.37)

0.18

21

0.43

 ISI

26,31

0.02

(− 0.33 to 0.38)

0.89

49

0.04

 BPI

31

0.49

(0.05 to 1.06)

0.03

NA

NA

Radiological outcomes nRCT

 HKA

17,21,33,36,39,41

− 0.08

(− 0.28 to 0.12)

0.44

0

0.85

 MAD

23

0.34

(− 0.08 to 0.74)

0.12

NA

NA

 MMPTA

23

0.06

(− 0.36 to 0.48)

0.79

NA

NA

 PTSA (AX)

16,21,23

− 0.19

(− 0.42 to 0.03)

0.09

34.4

0.23

 PTSA (PC)

12,18,22,38

− 0.16

(− 0.35 to 0.02)

0.08

39.4

0.18

 CDI

15,38,42

− 0.01

(− 0.21 to 0.20)

0.95

94

0.001

 ISI

22,38

− 0.20

(− 0.53 to 0.13)

0.23

0

0.43

 BPI

21,36,38

− 0.22

(− 0.50 to 0.06)

0.13

0

0.37

 AFTA

22,33,40

0.04

(− 0.66 to 0.74)

0.09

76.6

0.014

Clinical outcomes RCT

 ROM

24

0.08

(− 0.42 to 0.59)

0.75

NA

NA

 HSS

2,10,11

− 0.04

(− 0.294 to 0.22)

0.78

0

0.92

 KSS

24

0.15

(− 0.35 to 0.66)

0.55

NA

NA

 WOMAC

27,30

− 0.32

(− 0.72 to 0.07)

0.12

0

0.99

 VAS

10,13,24,27,30,31

− 0.11

(− 0.32 to 0.10)

0.23

4.2

0.39

Clinical outcomes nRCT

 ROM

21

0.28

(− 0.62 to 0.03)

0.08

NA

NA

 HSS

21,23

− 0.10

(− 0.39 to 0.19)

0.39

0

0.49

 KSS

23,36

− 0.05

(− 0.35 to 0.26)

0.76

0

0.47

 Lysholm score

13

− 0.34

(− 0.95 to 0.27)

0.28

NA

NA

CWHTO VS OWHTO in postoperative outcomes

Radiological outcomes RCT

 HKA

10, 24,26,27,30

0.21

(− 0.01 to 0.44)

0.06

0

0.83

 HKA CORRECTION

24,26,27

0.16

(− 0.13 to 0.46)

0.28

0

0.65

 MAD

26

0.45

(− 0.03 to 0.92)

0.065

NA

NA

 MMPTA

26

− 2.76

(− 3.42 to − 2.10)

0.001

NA

NA

 PTSA (AX)

24,26

− 1.32

(− 1.71 to − 0.94)

0.001

0

0.495

 CDI

27,30

0.82

(0.18 to 1.46)

0.012

59

0.547

 ISI

26,31

0.46

(0.09 to 0.82)

0.014

0

0.55

 BPI

31

0.49

(0.05 to 1.06)

0.03

NA

NA

Radiological outcomes nRCT

 HKA

17,21,33,36,39,41

− 0.04

(− 0.24 to 0.15)

0.67

0

0.71

 HKA CORRECTION

17

0.12

(− 0.39 to 0.63)

0.64

NA

NA

 MAD

23

0.32

(− 0.11 to 0.74)

0.14

NA

NA

 MMPTA

23

− 1.98

(− 2.34 to − 1.62)

0.001

NA

NA

 PTSA (AX)

16,21,23

− 1.19

(− 1.40 to − 0.99)

0.001

83.9

0.001

 PTSA (PC)

12,18,22,38

− 0.85

(− 1.04 to − 0.67)

0.001

92

0.001

 CDI

15,38,42

0.79

(0.55 to 1.03)

0.001

30

0.24

 ISI

22,38

0.06

(− 0.27 to 038)

0.74

0

0.99

 BPI

21,36,38

0.33

(0.04 to 0.70)

0.05

58.1

0.09

 AFTA

22,33,40

0.08

(− 0.23 to 0.39)

0.46

12.2

0.32

Clinical outcomes RCT

 VAS

10,13,24,27,30,31

− 0.11

(− 0.31 to 0.10)

0.30

33.8

0.18

 ROM

24

− 0.19

(− 0.70 to 0.32)

0.46

NA

NA

 HSS

10,24,31

0.12

(− 0.21 to 0.45)

0.49

38.4

0.20

 KSS

24

0.41

(− 0.01 to 0.93)

0.11

NA

NA

 WOMAC

27,30

− 0.42

(− 0.12 to 0.18)

0.09

13

0.346

Clinical outcomes nRCT

 Leg length change

16,37

− 1.33

(− 1.68 to − 0.97)

0.001

84.6

0.01

 ROM

43

− 0.36

(− 0.66 to 0.03)

0.06

NA

NA

 HSS

21,23

− 0.09

(− 0.38 to 0.20)

0.55

0

0.45

 KSS

23,31

0.09

(− 0.22 to 0.39)

0.58

0

0.52

 Lysholm score

13

− 0.38

(− 0.99 to 0.24)

0.23

NA

NA

  1. Postoperative results were compared between the two groups in the lower half of the table
  2. AX Anatomical axia, PC posterior cortex, RCT randomized controlled trial, nRCT non-randomized controlled trial, NA not available, ROM range of motion, HSS Hospital for Special Surgery Knee Score. KSS American Knee Society Score, VAS Visual Analog Scale Pain Score, WOMAC the total of Western Ontario and McMaster University Osteoarthritis Index, AFTA anatomical femorotibial angle, HKA hip-knee-ankle angle, MAD mechanical axis deviation, MMPTA mechanical medial proximal tibia angle, PTSA posterior tibial slope angle, CDI Caton-Deschamps Index, ISI Insall-Salvati Index, BPI Blackburne-Peel index