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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: The impact of cholesterol deposits on the fibrillar architecture of the Achilles tendon in a rabbit model of hypercholesterolemia

Fig. 3

Detection of CHP-accessible collagen α-chains. a, b H&E staining of the tendons from the nCH and the hCH rabbits. In addition, c and d demonstrate the CHP-positive signals in the consecutive sections observed using a fluorescence microscope. While the CHP-positive staining in the nCH samples is seen exclusively at the edges of the bundles of collagen fibers that form the tendon architecture, in the hCH samples, this staining is also seen across (large arrows) the longitudinal sections of the analyzed tendons. Besides, the DAPI staining corroborates a marked increase in the cellularity (small arrows) of the HCH tendons (d) in comparison with control (c)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X