Fig. 5
From: Combined low-dose LiCl and LY294002 for the treatment of osteoporosis in ovariectomized rats
Effects of LiCl, LY294002, and their combined application on BALP, PINP, TRACP-5b, and CTX in the serum of OVX rats (n = 3). Control: rats were subjected to sham surgery. OVX: rats were ovariectomized. LiCl: ovariectomized rats were injected with LiCl (10 mM). LY294002: ovariectomized rats were injected with LY294002 (10 μM). LiCl + LY294002: ovariectomized rats were injected with LiCl (5 mM) + LY294002 (5 μM). The serum was separated to measure the content of bone alkaline phosphatase (BALP) activity (a), the content of PION (b), the tartrate-resistant acid phosphatase isoform 5b (TRAP5b) activity (c), and the content of CTX (d). *P < 0.05 and **P < 0.01 denote statistically significant differences