Fig. 4

Changes in expression of the CD11b adhesion molecule on the surface of polymorphonuclear leukocytes (PMNs) expressed as mean fluorescence intensity values (a) and percentage of positive cells of the immune-labelled cells (b) within the gated PMN population. Values are shown at baseline and at 120 and 180 min of reperfusion after 60 min of limb ischemia in sham-operated (sham) and ovariectomized (OVX) rats treated with bisphosphonate (BIS) or a saline vehicle. Here, data values are given as means ± SEM, and *P < 0.05 vs baseline. Two-way RM ANOVA was followed by the Holm–Sidak and Dunn post hoc tests