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Table 2 Comparison of demographic and clinical characteristics and laboratory findings on ED arrival among NF patients with different concentrations of serum lactate

From: Lactate on emergency department arrival as a predictor of in-hospital mortality in necrotizing fasciitis: a retrospective study

Admission blood lactate, mmol/l

0.0–2.0

2.1–4.0

4.1–6.0

6.1–8.0

> 8.0

P value

n

145

275

141

84

62

 

Age, years

56.1 (30.1–68.9)

57.1 (35.9–71.2)

57.8 (33.8–75.1)

59.3 (41.9–79.2)

60.3 (42.3–85.6)

< 0.001

SBP at triage, mmHg

137.4 (115.8–175.6)

134.5 (115.4–189.7)

130.8 (106.8–174.3)

125.7 (105.2–170.9)

124.8 (103.6–168.7)

0.61

DBP at triage, mmHg

87.6 (51.8–120.5)

85.4 (52.4–117.9)

82.7 (50.7–115.6)

79.5 (42.7–114.2)

76.9 (40.9–108.1)

0.18

Episode of hypotension, n (%)

12 (10.3)

30 (10.9)

23 (16.3)

19 (22.6)

21 (33.9)

< 0.001

SOFA score

3 (0–6)

4 (0–6)

5 (1–7)

7 (2–9)

9 (4–16)

< 0.001

Hypothermia (BT < 36), n (%)

15 (10.3)

33 (12.0)

18 (12.8)

14 (13.1)

8 (12.5)

0.74

Hyperthermia (BT > =38), n (%)

33 (22.8)

70 (25.5)

28 (19.9)

17 (20.2)

11 (17.7)

0.56

Acidosis, n (%)

10 (6.9)

34 (12.4)

26 (18.4)

25 (29.8)

21 (33.9)

< 0.001

Coagulopathy, n (%)

16 (11.0)

36 (13.1)

22 (15.6)

17 (20.2)

15 (24.2)

< 0.001

Thrombocytopenia, n (%)

13 (9.0)

26 (9.5)

11 (7.8)

15 (17.9)

11 (18.4)

0.22

Anemia, n (%)

18 (12.4)

37 (13.5)

19 (13.5)

14 (16.7)

11 (18.5)

0.96

Episode of SpO2 < 90%, n (%)

11 (7.6)

25 (10.2)

17 (12.1)

11 (13.1)

7 (11.9)

0.77

In-hospital mortality, n (%)

3 (2.1)

6 (2.2)

7 (5.0)

11 (13.1)

13 (21.0)

< 0.001

Serum albumin (g/dl)

3.8 (2.6–4.1)

3.7 (2.4–4.6)

3.5 (2.1–3.9)

3.1 (2.1–3.5)

2.8 (1.8–3.4)

< 0.001

Serum creatinine (mg/dl)

1.1 (0.4–2.8)

1.3 (0.5–2.9)

1.7 (0.9–3.8)

2.1 (1.1–5.6)

2.5 (1.4–7.9)

< 0.01

Serum glucose (mg/dl)

128 (94–159)

136 (93–166)

158 (101–196)

169 (105–201)

184 (117–243)

< 0.01

Serum CRP (mg/dl)

98 (15–124)

112 (29–161)

135 (35–184)

169 (51–196)

198 (81–230)

< 0.01

Diabetes mellitus, n (%)

38 (26.2)

61 (24.9)

51 (36.1)

31 (36.9)

26 (42.3)

0.06

Liver cirrhosis, n (%)

24 (16.6)

45 (18.5)

32 (22.7)

29 (34.5)

24 (38.9)

0.08

Chronic kidney disease, n (%)

39 (26.9)

69 (28.2)

50 (35.5)

33 (39.3)

30 (48.7)

< 0.001

  1. Values are median [interquartile range]. Numbers in parentheses denote percentages
  2. CRP C-reactive protein, DBP diastolic blood pressure, SBP systolic blood pressure, SOFA sequential organ failure assessment