Table 1 Semi-quantitative histomorphometric scoring system as modified by Svensson, Soslowsky, and Cook
Parameter | Grade 0 | Grade 1 | Grade 2 | Grade 3 |
|---|---|---|---|---|
Fiber structure, Svenson and Solowsky scores | Normal parallel collagen fibers | Mild changes (< 25% slightly separated fibers) | Moderate changes (25–50% disorganized, separated, and deteriorated fibers) | Marked changes (> 50% disorganized and hyalinized fibers) |
Cellularity (aspect), Cook scores | Elongated nuclei and absence of cytosol | Oval nucleus and absence of cytosol | Round nucleus and little cytosol | Round nucleus and abundant cytosol |
Vascularity, Svensson score | Few vessels, parallel to the fiber | Slight increase of vessels | Moderate increase of vessels | Marked increase of vessels |
Cartilage formation | No cartilage | Isolated cartilage nodules | Moderate cartilage formation (25–50%) | Extensive cartilage formation (> 50%) |