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Table 1 Histological scoring system used to grade bone healing

From: Bovine bone particulates containing bone anabolic factors as a potential xenogenic bone graft substitute

Score

Bone defect coverage

New bone type

Vascularisation

Inflammation

Percentage of defect bridged by bone

Nature of new bone within defect

Presence of vascularisation within newly formed bone

Presence of inflammatory cells around newly formed bone

0

0%

No new bone

No evidence of neovascularisation

Abundant inflammation and evidence of encapsulation

1

1-24%

Predominantly woven

Few new vessels (<10)

Relatively few (10-50) inflammatory cells present

2

25-49%

Predominantly lamella remodelled

Abundant neovascularisation

No evidence of inflammatory cell presence

3

50-74%

-

-

-

4

75-100%

-

-

-