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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse

Fig. 1

Bone defect model and metabolic parameters. a The right mandible of the mouse was incised to completely expose the buccal and lingual side. b The mandible was made with a 1 mm × 1.5 mm defect across buccal to lingual. c The blood glucose level was above 16.9 mmol/l in HG and HFHG groups. d The TC, TG, LDL-C, and HDL-C levels in HF and HFHG groups increased significantly compared with NC and HG group. *p < 0.05, **p < 0.01, ***p < 0.001

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