Table 1 Basic information of 108 MM patients with vertebral pathological fracture (single factor analysis)
Characteristic | Surgery value N (%) or [SD] | Chemotherapy value N (%) or [SD] | P value |
|---|---|---|---|
Age | 60.81 [8.841] | 58.14 [8.225] | 0.108 |
Gender | 0.248 | ||
Male | 23 (44.2%) | 31 (55.4%) | |
Female | 2955.8%) | 25 (44.6%) | |
ISS staging | 0.529 | ||
ISS-I | 8 (15.4%) | 9 (16.1%) | |
ISS-II | 22 (42.3%) | 18 (32.1%) | |
ISS-III | 22 (42.3%) | 29 (51.8%) | |
Fracture quantity | 0.376 | ||
1 | 30 (57.6%) | 25 (44.6%) | |
2 | 11 (21.2%) | 17 (30.4%) | |
≥ 3 | 11 (21.2%) | 14 (25.0%) | |
Fracture location | 0.327 | ||
Cervical vertebra | 0 (0.0%) | 0 (0.0%) | |
Thoracic vertebra | 18 (34.6%) | 24 (42.9%) | |
Lumbar vertebra | 24 (46.2%) | 18 (32.1%) | |
Short segment | 10 (19.2%) | 14 (25.0%) | |
Stem cell transplantation | 9 (17.3%) | 18 (32.1%) | 0.075 |
VAS initial | 7.79 [0.637] | 7.86 [0.903] | 0.651 |
VAS post-treated | |||
1 month | 2.65 [0.683] | 3.55 [0.893] | 0.000 |
Mean change at 1 month | 5.13 [0.971] | 4.30 [0.952] | 0.00 |
Last follow-up | 3.27 [0.744] | 4.77 [1.279] | 0.000 |
Mean change at last follow-up | 4.52 [0.960] | 3.09 [1.180] | 0.000 |
ODI initial | 0.72 [0.127] | 0.74 [0.149] | 0.381 |
ODI post-treated | |||
1 month | 0.19 [0.072] | 0.29 [0.116] | 0.000 |
Mean change at 1 month | 0.53 [0.156] | 0.45 [0.146] | 0.009 |
Last follow-up | 0.36 [0.094] | 0.35 [0.101] | 0.719 |
Mean change at last follow-up | 0.36 [0.143] | 0.39 [0.149] | 0.284 |
Activity disorder | 4 (7.7%) | 13 (23.2%) | 0.027 |
Overall survival (month) | 41.98 [22.168] | 42.91 [21.312] | 0.825 |
Mortality rate | |||
1 year | 4 (7.7%) | 1 (1.8%) | 0.144 |
2 years | 10 (19.2%) | 12 (21.4%) | 0.777 |
3 years | 22 (42.3%) | 23 (41.1%) | 0.896 |
Cause of death | 3 people died of pneumonia (13.6%), 18 people died of disease progression (81.8%), 1 person died of hemorrhage of the digestive tract (4.5%) | 10 people died of pneumonia (43.5%), 13 people died of disease progression (56.5%) | 0.027 |