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Table 2 Association of risk factors and comorbidities with all-type, mechanical, and complications due to infections after total joint arthroplasty (TJA)

From: Identification of high-risk groups for complication after arthroplasty: predictive value of patient’s related risk factors

  All type complications (n = 92) Mechanical complicationa (n = 43) Infection complicationb (n = 38)
HR (95%CI) P HR (95%CI) P HR (95%CI) P
Risk factors
 Age 1.00 (0.98–1.02) 0.99 0.99 (0.97–1.02) 0.49 1.00 (0.97–1.03) 0.98
 Gender (female) 0.94 (0.63–1.40) 0.75 0.85 (0.46–1.57) 0.61 1.30 (0.65–2.60) 0.46
 Smoking 1.29 (0.85–1.97) 0.23 1.14 (0.51–2.56) 0.75 1.64 (0.72–3.74) 0.24
 Alcohol 1.22 (0.74–2.02) 0.44 1.39 (0.54–3.55) 0.50 0.84 (0.25–2.85) 0.78
 Corticosteroids 2.14 (1.163.92) 0.01 1.68 (0.60–4.75) 0.33 3.16 (1.397.22) 0.006
Comorbidities
 Diabetes 1.42 (0.93–2.15) 0.10 1.10 (0.56–2.16) 0.79 2.32 (1.184.57) 0.02
 Obesity 1.15 (0.56–2.34) 0.70 1.72 (0.87–3.39) 0.12 1.58 (0.72–3.47) 0.26
 Respiratory 2.35 (1.393.97) 0.001 0.94 (0.29–3.12) 0.94 4.55 (2.0310.2) < 0.001
 Anemia 2.46 (1.075.70) 0.04 NA NA 4.93 (1.90–12.8) 0.001
 Osteoporosis 1.34 (0.85–2.12) 0.21 1.83 (0.94–3.56) 0.08 1.08 (0.50–2.35) 0.84
 Infectious 1.91 (1.133.23) 0.02 1.51 (0.64–3.60) 0.35 3.09 (1.506.40) 0.002
 Musculoskeletal 1.42 (0.92–2.18) 0.12 2.11 (1.133.96) 0.02 1.15 (0.56–2.37) 0.71
 Hernia (all-type) 1.84 (0.98–3.44) 0.06 3.93 (1.778.72) 0.001 NA NA
 Mental 2.16 (1.243.75) 0.03 1.14 (0.35–3.72) 0.83 2.50 (1.095.70) 0.05
 Gastrointestinal 1.12 (0.52–2.42) 0.78 1.18 (0.36–3.84) 0.79 0.87 (0.27–2.83) 0.82
 Cancer 0.74 (0.24–2.35) 0.62 0.59 (0.08–4.30) 0.60 1.33 (0.32–5.60) 0.70
 Cardiovascular 1.12 (0.69–1.80) 0.65 0.90 (0.41–1.97) 0.79 1.02 (0.47–2.24) 0.96
 Others 1.89 (1.233.90) 0.004 1.99 (1.03–3.85) 0.04 1.65 (0.82–3.34) 0.16
 TKA 0.93 (0.62–1.40) 0.73 0.41 (0.190.87) 0.02 2.18 (1.114.29) 0.02
 RA 3.81 (2.306.31) < 0.001 3.25 (1.467.25) 0.004 5.98 (2.9312.2) < 0.001
  1. TKA total knee arthroplasty (compared to THA), RA rheumatoid arthritis. All variables were adjusted for age/gender, any kind of infection, including urinary tract and respiratory infections
  2. aMechanical complication: dislocation, osteolysis in prosthesis with less than 6 years old, loss of implant fixation, implant failure, fracture
  3. bInfection-complication: superficial and deep infections, called prosthetic joint infections (PJI). In italic all significant factors (P value < 0.05)