Table 1 VCM concentrations (mean ± SD) and minimum VCM bioactivities
| Â | Day | 1 | 3 | 7 | 14 | 28 | 56 | 84 |
|---|---|---|---|---|---|---|---|---|
D-L spacer (μg/mL) | VCM concentration measured by HPLC | 1415.3 (± 346.9) | 175.6 (± 76.2) | 152.8 (± 45.2) | 109.3 (± 29.3) | 59.5 (± 16.1) | 29.4 (± 10.8) | 22.6 (± 7.3) |
Minimum VCM bioactivity | > 320 | 160 | 160 | 80 | 40 | 20 | 20 | |
PMMA spacer (μg/mL) | VCM concentration measured by HPLC | 1580.1 (± 1312.9) | 179.5 (± 81.1) | 66.1 (± 45.5) | 19.4 (± 10.3) | 8.5 (± 4.6) | 3.1 (± 1.2) | 1.9 (± 0.7) |
Minimum VCM bioactivity | > 320 | 160 | 40 | 10 | 2.5 | 0 | 0 |