Table 1 VCM concentrations (mean ± SD) and minimum VCM bioactivities
| Day | 1 | 3 | 7 | 14 | 28 | 56 | 84 | |
|---|---|---|---|---|---|---|---|---|
|
D-L spacer (μg/mL) |
VCM concentration measured by HPLC |
1415.3 (± 346.9) |
175.6 (± 76.2) |
152.8 (± 45.2) |
109.3 (± 29.3) |
59.5 (± 16.1) |
29.4 (± 10.8) |
22.6 (± 7.3) |
|
Minimum VCM bioactivity | > 320 | 160 | 160 | 80 | 40 | 20 | 20 | |
|
PMMA spacer (μg/mL) |
VCM concentration measured by HPLC |
1580.1 (± 1312.9) |
179.5 (± 81.1) |
66.1 (± 45.5) |
19.4 (± 10.3) |
8.5 (± 4.6) |
3.1 (± 1.2) |
1.9 (± 0.7) |
|
Minimum VCM bioactivity | > 320 | 160 | 40 | 10 | 2.5 | 0 | 0 |
