Kinetic of bone turnover markers after osteoporotic vertebral compression fractures in postmenopausal female

Table 1 Comparisons of bone turnover markers and others at different periods of time after OVCFs

Variables	Group 1	Group 2	Group 3	Group 4	Group 5	Group 6	Group 7	P
Number	40	46	37	35	75	38	38
Age (years)	67.1 ± 8.8	71.0 ± 8.9	70.7 ± 9.3	68.1 ± 7.8	68.5 ± 7.4	69.9 ± 7.4	67.6 ± 7.6	0.204
BMD (g/cm²)	0.74 ± 0.19	0.69 ± 0.17	0.78 ± 0.14	0.78 ± 0.12	0.70 ± 0.15	0.70 ± 0.20	0.77 ± 0.11	0.138
Osteocalcin (ng/ml)	16.6 ± 4.8	21.4 ± 5.6	19.2 ± 4.6	20.5 ± 5.5	23.7 ± 6.5	25.8 ± 7.5	21.1 ± 7.1	< 0.001
β-CTX (ng/ml)	0.61 ± 0.17	0.72 ± 0.17	0.68 ± 0.17	0.79 ± 0.22	0.84 ± 0.28	0.89 ± 0.23	0.65 ± 0.27	< 0.001
ALP (U/L)	86.0 ± 18.0	91.5 ± 17.8	100.7 ± 20.9	123.9 ± 25.7	111.7 ± 20.5	106.0 ± 23.1	97.8 ± 26.4	< 0.001
PINP (ng/ml)	47.8 ± 13.4	52.6 ± 13.2	54.3 ± 10.1	62.1 ± 15.6	69.3 ± 21.3	69.5 ± 16.8	58.2 ± 18.6	< 0.001
Calcium (mmol/L)	2.27 ± 0.09	2.29 ± 0.09	2.30 ± 0.07	2.28 ± 0.07	2.34 ± 0.08	2.28 ± 0.07	2.27 ± 0.14	0.001
Phosphorus (mmol/L)	1.12 ± 0.13	1.21 ± 0.13	1.15 ± 0.10	1.23 ± 0.09	1.23 ± 0.13	1.20 ± 0.09	1.18 ± 0.13	< 0.001

OVCFs osteoporotic vertebral compression fractures, BMD bone mineral density, β-CTX β-isomerized C-terminal telopeptides, ALP alkaline phosphatase, PINP type I procollagen amino- terminal peptides

ISSN: 1749-799X