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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: The potent anti-inflammatory effect of Guilu Erxian Glue extracts remedy joint pain and ameliorate the progression of osteoarthritis in mice

Fig. 1

Tactile sensitivity in ACLT-induced OA-related allodynia. Von Frey testing was used to measure the response evoked by mechanical stimulus in the groups treated with GE-P (100 and 300 mg/kg/day), GE-L (100 and 300 mg/kg/day), and celecoxib (10 mg/kg/day) when compared to the saline group. Mechanical hyperalgesia was tested by observing the changes in tactile sensitivity (pain behavior) on day 28, before sacrifice. Paw withdrawal threshold (PWT) was significantly reduced in the saline-treated ACLT mice (**p < 0.01) when compared with the vehicle controls. Each value represents the mean values obtained from 10 mice in two different experimental sets. *p < 0.05 and **p < 0.01 denote significant differences when compared with the vehicle control (sham). #p < 0.05 and ##p < 0.01 denote significant differences when compared with the saline-treated (ACLT) mice

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