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Table 2 Subgroup analysis of serum COMP with different unit of measure and disease severity

From: Correlation of serum cartilage oligomeric matrix protein with knee osteoarthritis diagnosis: a meta-analysis

Subgroups

Number of study

Mean difference

95% CI

P

Unit of measure

 U/L

3

2.13

0.11, 4.16

0.04

 μg/ml

6

1.00

0.37, 1.63

0.002

Disease severity

 K-L 1 VS K-L 2

3

0.79

0.34, 1.25

0.0007

 K-L 1 VS K-L 3

3

1.08

0.44, 2.60

0.16

 K-L 1 VS K-L 4

3

1.61

0.57, 2.65

0.002

 K-L 2 VS K-L 3

6

0.44

0.04, 0.85

0.03

 K-L 2 VS K-L 4

7

0.61

0.17, 1.05

0.007

 K-L 3 VS K-L 4

5

0.41

0.15, 0.68

0.002

  1. K-L Kellgren-Lawrence classification, CI confidence intervals