Efficacy of intravenous acetaminophen in multimodal management for pain relief following total knee arthroplasty: a meta-analysis

Table 1 General characteristic of the included studies

Author	Country	Age (year)	Study	Dose of acetaminophen	Control	Follow-up	Anesthesia
Kelly [15]	America	63.9/65.3	RCS	1000 mg/day	Placebo	NS	NS
Nwagbologu [17]	Mexico	61/63.9	RCS	1000 mg/day	Placebo	3 days	NS
O’Neal [18]	America	68/70	RCT	1000 mg/day	Placebo	NS	SA
Murata-Ooiwa [19]	Japan	73.6/75.3	RCT	1000 mg/day	Placebo	3 days	SA
Ciummo [23]	America	NS	RCS	NS	Placebo	NS	NS
Huang [21]	America	71.3/71.6	RCS	4000 mg/day	Placebo	3 days	SA/GA

RCT randomized controlled trials, RCS retrospective controlled studies, NS not stated, SA spinal anesthesia, GA general anesthesia

ISSN: 1749-799X