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Table 3 Subgroup analysis according to study sites

From: Adjacent segment degeneration or disease after cervical total disc replacement: a meta-analysis of randomized controlled trials

SITE

U.S.

CHINA

 

OR [95%CI]

P value

I2(%)

NO. of P

NO. of ASD

NO. of S

OR [95%CI]

P value

I2(%)

NO. of P

NO. of ASD

NO. of S

ASDeg

0.59 [0.46, 0.75]

0.0001

44

1184

463

4

0.52 [0.29, 0.92]

0.03

0

240

78

3

ASDis

0.99 [0.57, 1.73]

0.98

0

738

61

3

–

–

–

–

–

0

Reop

0.56 [0.32, 0.96]

0.03

11

1676

57

4

0.11 [0.01, 2.00]

0.13

–

111

4

1

  1. Abbreviations: FU follow-up, ASDeg adjacent segment degeneration, ASDis adjacent segment disease, Reop Reoperation, NO. of P the number of patients, NO. of ASD the number of ASD, NO. of S the number of studies