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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Combined detection of COMP and CS846 biomarkers in experimental rat osteoarthritis: a potential approach for assessment and diagnosis of osteoarthritis

Fig. 1

Macroscopic observation of tibial plateau. a Tibial plateau of rats in the control group showed a smooth cartilage surface, and no cartilage defects or osteophytes. b After 2 weeks of surgery, the joint surface was slightly rough (arrow). c The joint surface was partially recessed at 4 weeks of after surgery (arrow). d The joint surface was rough and matte at 6 weeks of after surgery (rectangle frame). e The articular cartilage was severely damaged at 8 weeks after surgery (rectangle frame). f The joint surface showed a large area of ulcers, and subchondral bone was exposed at 10 weeks after surgery (arrow)

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