Fig. 1
From: An evaluation of anesthetic fade in motor evoked potential monitoring in spinal deformity surgeries
Schema of the time course. Time 0 was defined as when the infusion of propofol started. Muscle relaxant was administered only upon propofol induction. A small amount of inhalation anesthetic (sevoflurane, 0.8 to 8.0%) was used for anesthetic induction in 44 pediatric cases. Anesthesia was maintained with continuous infusion of propofol and remifentanil. Star marker, start of surgery; MEP, motor evoked potential; TCI, target-controlled infusion (a device to deliver the drug to achieve specific predicted target drug concentrations in the blood); BIS, bispectral index (a device to assess the depth of anesthesia)