| | Control (n = 10) | T(1) (n = 10) | ZA (n = 10) | T(1)+ZA (n = 10) | T(10)+ZA (n = 10) | ANOVA |
|---|
Fusion rate (%) | 20.0 | 55.6 | 70.0 | 70.0 | 80.0 | |
4-point scale | 0.50 ± 0.85 | 1.56 ± 1.67 | 2.00 ± 1.41 | 2.60 ± 1.90a | 2.80 ± 1.69a | 0.014 |
- All values are mean ± standard deviation
- Evaluation of femoral shaft fracture was performed with Softex X-ray apparatus. Fracture union was judged by visual assessment of the mineralized callus bridging the fracture line in the A-P radiographs (right side: 1 point; left side: 1 point) and lateral radiographs (anterior side: 1 point; posterior side: 1 point). The bone fusion was considered to be more than 2 points with soft X-ray images on a 4-point scale. About the bone fusions rates, C, T(1), ZA, T(1)+ZA group, and T(10)+ZA group demonstrated 20.0%, 55.6%, 70.0%, 70.0%, and 80.0% respectively. With the 4-point scale analysis, T(10)+ZA and T(1)+ZA groups were significantly superior to C group in bone union
- T(1) teriparatide 1 μg group, ZA zoledronate group, T(1)+ZA teriparatide 1 μg + zoledronate group, T(10)+ZA teriparatide 10 μg + zoledronate group
- ap < 0.05 vs. control group, by post hoc test
