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Table 3 Diagnostic performance of US and MRI for evaluating cartilaginous defects on different surfaces

From: A novel ultrasound scanning approach for evaluating femoral cartilage defects of the knee: comparison with routine magnetic resonance imaging

Surface

TP#

TN#

FP#

FN#

Sensitivity (95%CI) (%)

Specificity (95%CI) (%)

Accuracy (95%CI) (%)

Crude predictive value (95%CI) (%)

Adjusted predictive value (%)

AUC (95%CI)

PPV

NPV

PPV

NPV

 

US Radiologist 1

 TS

31

25

2

7

81.6 (69.3–93.9) (0.317)

92.6 (82.7–102) (1.000)

86.2 (77.8–94.6) (1.000)

93.9 (85.5–102) (1.000)

78.1 (63.8–92.4) (1.000)

92.2

82.3

0.871 (0.791–0.951)

 MC

20

22

3

20

50.0 (34.5–65.5) (0.005)

88.0 (75.3–101) (0.046)

64.6 (53.0–76.2) (0.058)

87.0 (73.2–100) (0.310)

52.4 (37.3–67.5) (0.251)

81.8

62.0

0.690 (0.588–0.792)

 LC

18

31

1

15

54.5 (37.6–71.5) (0.083)

96.9 (90.8–103) (0.317)

75.4 (64.9–85.9) (0.046)

94.7 (84.7–105) (1.000)

67.4 (53.8-80.9) (0.818)

95.0

66.4

0.757 (0.666–0.849)

US Radiologist 2

 TS

35

24

3

3

92.1 (83.5–101) (0.025)

88.9 (77.0–101) (0.317)

90.8 (83.7–97.8) (0.424)

92.1 (83.5–101) (1.000)

88.9 (77.0–101) (0.315)

90.0

91.3

0.905 (0.831–0.979)

 MC

22

22

3

18

55.0 (39.6–70.4) (0.248)

88.0 (75.3–101) (0.014)

67.7 (56.3–79.1) (0.157)

88.0 (75.3–101) (0.424)

55.0 (39.6–70.4) (0.352)

83.2

64.4

0.715 (0.613–0.817)

 LC

20

30

2

13

60.6 (43.9–77.3) (1.000)

93.8 (85.4–102) (0.317)

76.9 (66.7–87.2) (1.000)

90.9 (78.9–103) (0.424)

69.8 (56.0–83.5) (1.000)

91.3

68.8

0.772 (0.677–0.867)

MRI

 TS

30

25

2

8

78.9 (66.0–91.9)

92.6 (82.7–102)

84.6 (75.8–93.4)

93.8 (85.4–102)

75.8 (61.1–90.4)

92.0

80.3

0.858 (0.775–0.940)

 MC

28

24

1

12

70.0 (55.8–84.2)

96.0 (88.3–104)

80.0 (70.3–89.7)

96.6 (89.9–103)

66.7 (51.3–82.1)

95.0

74.8

0.830 (0.748–0.712)

 LC

21

30

2

12

63.6 (47.2–80.0)

93.8 (85.4–102)

78.5 (68.5–88.5)

91.3 (79.8–103)

71.4 (57.8–85.1)

91.7

70.5

0.787 (0.693–0.881)

  1. Numbers in parentheses are the P values compared to MRI data (McNemar test)
  2. TS trochlear surface, MC medial condyles, LC lateral condyles, TP true positive, TN true negative, FP false positive, FN false negative
  3. #Data are the surface numbers