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Table 1 Demographics, comorbidities and pre-operative, perioperative and post-operative values (6 weeks) in non-TXA and TXA groups

From: Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study

 

Non-TXA

TXA

p value

Age (years)

69 ± 1

65 ± 1

0.092

Weight (kg)

91 ± 5

90 ± 6

0.930

No. of patients

11

12

 

Gender

M = 4

M = 2

 

F = 7

F = 10

 

Osteoarthritis

11

12

 

TXA administration:

 IV Infusion (mg/kg)

NA

13.5 ± 0.6

 

 IA Injection (mg/kg)

NA

15.5 ± 0.7

 

Preoperative:

 Hemoglobin (HgB) g/L

136 ± 4

137 ± 4

0.980

Anesthetic:

 General only

0

1

 

 General + Spinal

11

11

 

Perioperative:

 Tourniquet time (Min)

62 ± 11

27 ± 6

0.023*

 Surgical time (Min)

107 ± 6

104 ± 4

0.566

Postoperative:

 HgB g/L day 1

121 ± 3§

122 ± 3§

0.787

 HgB g/L day 2

111 ± 2§

121 ± 5§

0.093

  1. Data represent mean ± SEM *p < 0.05 between non-TXA and TXA group;
  2. §p < 0.05 compared to preoperative value