Fig. 3

Plasma levels of inflammatory cytokine/chemokines a MCP-1, b TNF-α, c IL-1RA, d IL-1β, e IL-8, f IL-6, g IL-4, and h IL-10 at baseline, after bone cuts, surgery end, day 1 and day 2. White square: non-TXA group; black square: TXA group. Data is expressed as mean ± S.E.M. *p < 0.05 compared with corresponding non-TXA patients, ^◆p < 0.05 compared to baseline, bone cut, end surgery and day 1, ^†p < 0.05 compared to baseline, bone cut and end surgery; ^#p < 0.05 compared to baseline; ^∫p < 0.05 compared to end surgery and day 1; ^§p < 0.05 compared to bone cut; ^{^}p < 0.05 compared to baseline and bone cut