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Table 2 Relationship between the serum levels of the three biomarkers and sex

From: Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease

Biomarker
(ng/ml)
Sex KBD Internal control External control H P
Median P25,P75 Median P25,P75 Median P25,P75
PIICP Male 33.38 20.75,46.63 53.03 39.94,75.02 61.12 22.53,97.48 9.83 0.007
Female 30.90 9.08,65.02 51.77 30.69,103.00 82.75 23.64,134.95 14.74 0.001
PIIANP Male 65.61 56.79,91.42 98.85 74.09,152.67 80 57.12,160 9.71 0.008
Female 65.37 48.60,89.36 92.98 67.57,151.66 80.40 67.66,114.52 12.87 0.002
PIIBNP Male 17.15 11.29,24.19 30.63 21.89,40.54 26.82 11.99,47.41 11.39 0.003
Female 11.61 4.79,32.39 25.90 19.43,47.78 41.24 12.06,54.89 14.00 0.001