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Table 2 Relationship between the serum levels of the three biomarkers and sex

From: Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease

Biomarker

(ng/ml)

Sex

KBD

Internal control

External control

H

P

Median

P25,P75

Median

P25,P75

Median

P25,P75

PIICP

Male

33.38

20.75,46.63

53.03

39.94,75.02

61.12

22.53,97.48

9.83

0.007

Female

30.90

9.08,65.02

51.77

30.69,103.00

82.75

23.64,134.95

14.74

0.001

PIIANP

Male

65.61

56.79,91.42

98.85

74.09,152.67

80

57.12,160

9.71

0.008

Female

65.37

48.60,89.36

92.98

67.57,151.66

80.40

67.66,114.52

12.87

0.002

PIIBNP

Male

17.15

11.29,24.19

30.63

21.89,40.54

26.82

11.99,47.41

11.39

0.003

Female

11.61

4.79,32.39

25.90

19.43,47.78

41.24

12.06,54.89

14.00

0.001