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Table 3 Meta-analysis results

From: The efficacy and safety of topical administration of tranexamic acid in spine surgery: a meta-analysis

Outcome

Studies

Groups (A/C)

Overall effect

Heterogeneity

Effect estimate

95% CI

p value

I2 (%)

p value

Total blood loss

2

66/64

− 267.53

− 373.04, − 106.02

0.00001

0

0.38

Drainage volume

4

136/134

− 157.00

− 191.17, − 122.84

0.00001

42

0.16

Blood transfusion rate

4

136/134

− 0.18

− 0.51, 0.15

0.28

94

0.00001

Postoperative hemoglobin level

2

80/80

0.95

0.44, 1.47

0.0003

0

0.43

Hematoma

3

120/120

0.00

− 0.03, 0.03

1.00

0

1.00

Infection

3

120/120

0.00

− 0.03, 0.03

1.00

0

1.00

Deep Vein Thrombosis

2

90/90

0.00

− 0.03, 0.03

1.00

0

1.00

Pulmonary embolism

2

90/90

0.00

− 0.03, 0.03

1.00

0

1.00

Length of hospital stay

2

70/70

− 1.42

− 1.92, − 0.93

0.00001

79

0.03

  1. A aminocaproic acid, C control, CI confidence interval