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Table 3 Meta-analysis results

From: The efficacy and safety of topical administration of tranexamic acid in spine surgery: a meta-analysis

Outcome Studies Groups (A/C) Overall effect Heterogeneity
Effect estimate 95% CI p value I2 (%) p value
Total blood loss 2 66/64 − 267.53 − 373.04, − 106.02 0.00001 0 0.38
Drainage volume 4 136/134 − 157.00 − 191.17, − 122.84 0.00001 42 0.16
Blood transfusion rate 4 136/134 − 0.18 − 0.51, 0.15 0.28 94 0.00001
Postoperative hemoglobin level 2 80/80 0.95 0.44, 1.47 0.0003 0 0.43
Hematoma 3 120/120 0.00 − 0.03, 0.03 1.00 0 1.00
Infection 3 120/120 0.00 − 0.03, 0.03 1.00 0 1.00
Deep Vein Thrombosis 2 90/90 0.00 − 0.03, 0.03 1.00 0 1.00
Pulmonary embolism 2 90/90 0.00 − 0.03, 0.03 1.00 0 1.00
Length of hospital stay 2 70/70 − 1.42 − 1.92, − 0.93 0.00001 79 0.03
  1. A aminocaproic acid, C control, CI confidence interval