Imaging diagnosis for chronic lateral ankle ligament injury: a systemic review with meta-analysis

Table 3 Results of pooled data

Test	Ligament	Studies	Participants	TP	FP	FN	TN	Pooled sensitivity		Pooled specificity		Pooled LR+		Pooled LR−		Pooled DOR
Test	Ligament	Studies	Participants	TP	FP	FN	TN	Value [95%CI]	I ²	Value [95%CI]	I ²	Value [95%CI]	I ²	Value [95%CI]	I ²	Value [95%CI]	I ²
MRI	ATFL	12	457	300	19	68	70	0.83 [0.78, 0.87]	50.4%	0.79 [0.69, 0.87]	68.6%	2.72 [1.41–5.24]	60.4%	0.28 [0.19–0.41]	20.7%	16.25 [7.65–34.53]	0.0%
MRI	CFL	7	269	58	20	45	146	0.56 [0.46, 0.66]	30.5%	0.88 [0.82, 0.93]	48.9%	3.84 [1.99–7.40]	36.5%	0.55 [0.41–0.74]	38.8%	8.28 [3.08–22.24]	48.7%
US	ATFL	4	246	177	6	2	61	0.99 [0.96, 1.00]	0%	0.91 [0.82, 0.97]	71.6%	15.08 [5.85–38.87]	0%	0.02 [0.00–0.07]	0%	946.51 [159.33–5622.80]	0%
US	CFL	1	120	61	5	4	50	0.94 [0.85, 0.98]	–	0.91 [0.80, 0.97]	–	10.3 [4.5–23.9]	–	0.07 [0.03–0.18]	–	153 [7–3550]	–
stress radiography	ATFL	4	118	66	3	14	35	0.81 [0.68, 0.90]	44.9%	0.92 [0.79, 0.98]	0%	7.94 [3.11–20.28]	0%	0.24 [0.11–0.54]	46%	39.24 [10.50–146.56]	0%
stress radiography	CFL	2	95	24	5	7	59	0.77 [0.59, 0.90]	86.6%	0.92 [0.83, 0.97]	75.7%	9.88 [0.65–149.20]	83.8%	0.20 [0.01–4.14]	89.3%	53.40 [0.50–5752.7]	88.2%
Arthrography	ATFL	2	34	28	0	0	6	1.00 [0.88, 1.00]	0%	1.00 [0.54, 1.00]	0%	–	–	–	–	–	–
Arthrography	CFL	3	70	26	4	3	37	0.90 [0.73, 0.98]	0%	0.90 [0.77, 0.97]	26.5%	7.55 [3.15–18.05]	0%	0.15 [0.06–0.39]	0%	69.85 [13.77–354.41]	0%

Abbreviation: US ultrasonography, ATFL anterior talofibular ligament, CFL calcaneofibular ligament, TP true positive, FP false positive, FN false negative, TN true negative, LR+ positive likelihood ratio, LR− negative likelihood ratio, DOR diagnostic odds ratio

ISSN: 1749-799X