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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Bi-directional regulation of cartilage metabolism by inhibiting BET proteins—analysis of the effect of I-BET151 on human chondrocytes and murine joints

Fig. 1

The effect of BET protein inhibitor on the severity of OA in a surgical mouse model of OA. a Representative Safranin-O-stained sections of the knees from test and control group, 6 weeks after surgery DMM. b Histological assessments of OA on femoral and tibial cartilage by OARSI histopathology grading, 6 weeks after surgery DMM (n = 10). c Representative Safranin-O-stained sections of knees from test and control group, 8 weeks after surgery DMM. d Histological assessments of OA on femoral and tibial cartilage by OARSI histopathology grading, 8 weeks after surgery DMM (n = 10)

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