Table 2 Demographic, clinical, and imaging characteristics of the 26 patients with SAPHO syndrome
Age at onset (years) | 44.6 ± 11.1 |   SS | 5 (19.2%) |
Gender, female | 20 (74.1%) |   Ilium | 4 (15.4%) |
Age at performing PET/CT, years | 47.9 ± 10.8 |   CS | 4 (15.4%) |
Skin lesions | 25 (96.2) |   Phalanx | 2 (7.7%) |
 PPP | 23 (88.5%) |   Shoulder | 1 (3.8%) |
 SA | 4 (15.4%) |   Femur | 1 (3.8%) |
 PV | 2 (7.7%) |  SUVmax | 6.0 ± 3.4 |
Osteoarticular symptoms | 26 (100%) |  Site of lesions on CT |  |
 Anterior chest pain | 26 (100%) |   ACW | 17 (65.4%) |
 Cervical region pain | 6 (23.1%) |   LS | 13 (50.0%) |
 Thoracic region pain | 12 (46.2%) |   TS | 10 (38.5%) |
 Lumbosacral region pain | 21 (80.8%) |   SI | 6 (23.1%) |
 Hip pain | 9 (34.6%) |   SS | 6 (23.1%) |
 Others | 6 (19.2%) |   Ilium | 4 (15.4%) |
Laboratory findings |  |   CS | 4 (15.4%) |
ESR, mm/h | 46.9 ± 8.2 |   Phalanx | 3 (11.5%) |
CRP, mg/L | 22.4 ± 7.9 |   Posterior rib | 1 (3.8%) |
HLA-B27, positive | 0 (0%) |  Characteristics of lesions on CT |  |
Bone scintigraphy | 25 |   Osteolysis | 16 (61.5%) |
 ACW | 25 (100%) |   Osteosclerosis | 10 (38.5%) |
 LS | 16 (61.5%) |   Hyperostosis | 8 (30.8%) |
 TS | 12 (46.2%) |   Soft tissue edema | 5 (19.2%) |
 SI | 8 (32.0%) |   Joint space widening | 3 (11.5%) |
 CS | 4 (16.0%) |   Osteophyte | 2 (7.7%) |
 SS | 3 (12.0%) |   Increased BMD | 2 (7.7%) |
 Femur | 2 (8.0%) |   Heterogeneous BMD | 2 (7.7%) |
 Ilium | 2 (8.0%) |   Decreased BMD | 2 (7.7%) |
 Knee | 2 (8.0%) |   Increased and decreased BMD | 1 (3.8%) |
 Other | 5 (19.2%) |   Others | 3 (11.5%) |
PET/CT |  |  Extra-osteoarticular abnormalities | 19 (73.1%) |
 Osteoarticular abnormalities | 26 (100%) |   Tonsil, pharynx, nose, paranasal sinus | 10 (38.5%) |
 Sites of increased tracer uptake |  |   Lymph node | 8 (30.8%) |
  ACW | 23 (88.5%) |   Thyroid gland | 5 (19.2%) |
  LS | 15 (57.7%) |   Gastrointestinal tract | 4 (15.4%) |
  TS | 11 (42.3%) |   Lung and pleura | 2 (7.7%) |
  SI | 7 (26.9%) |   Others | 1 (3.8%) |