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Table 2 Genotype and allele frequencies of FTO polymorphism (rs8044769) in Han Chinese population

From: FTO variant is not associated with osteoarthritis in the Chinese Han population: replication study for a genome-wide association study identified risk loci

Subjects

N

Allele

P value

Phet

OR (95% CI)

Genotype

P value

C (%)

T (%)

CC (%)

CT (%)

TT (%)

Cases

890

1096 (61.57)

684 (38.43)

0.436

Ā 

0.947 (0.825ā€“1.086)

333 (37.41)

430 (48.32)

127 (14.27)

0.438

Controls

844

1061 (62.85)

627 (37.14)

Ā Ā Ā 

339 (40.16)

383 (45.38)

122 (14.46)

Ā 

Combined with another Chinese group

Ā 

ā€ƒCases

890ā€‰+ā€‰1093

1096ā€‰+ā€‰233 (61.36)

684ā€‰+ā€‰153 (38.64)

0.478*

0.745**

0.958* (0.849ā€“1.079)

Ā 

ā€ƒControls

844ā€‰+ā€‰436

1061ā€‰+ā€‰528 (62.07)

627ā€‰+ā€‰344 (37.93)

Ā Ā Ā Ā 
  1. *P value and odds ratio were calculated by Mantel-Haenszel test, **P for heterogeneity