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Table 1 Changes in Enhancement Percentage at Center of Disc and histologic scores of endplate in different age groups in rats

From: Non-invasive quantification of age-related changes in the vertebral endplate in rats using in vivo DCE-MRI

Age group Discs in L3–L4 Discs in L4–L5 Discs in L5–L6 Discs in L6–S1 Histologic score (0–18)
3-month-old 54.54 ± 5.81 47.69 ± 13.36 48.79 ± 11.45 43.56 ± 12.95 2.67 ± 0.52
6-month-old 44.14 ± 8.35* 44.84 ± 6.21 43.65 ± 9.92 29.26 ± 5.04* 9.50 ± 1.05*,**
9-month-old 40.96 ± 4.57 36.45 ± 6.12 34.29 ± 7.13 25.43 ± 6.85* 14.17 ± 1.72*
  1. Values are expressed as the mean ± SD. Enhancement Percentage = (the maximum signal intensity postenhancement (SImax) − the signal intensity from baseline (SIbase))/SIbase × 100 (L3–L4 represent the intervertebral disc between the third and the fourth lumbar vertebra, and so on)
  2. *P < 0.05 compared with 3-month-old groups
  3. **P < 0.05 the histologic changes for the endplate of 6-month-old compared with 9-month-old group