The efficacy of tranexamic acid using oral administration in total knee arthroplasty: a systematic review and meta-analysis

Table 2 Characteristics of included studies showing general intervention information

Studies (year)	Dosage of TXA (mg)	Surgical approach	Transfusion criteria	Postoperative anticoagulation	Surgery	Anesthesia	DVT screening method	Pneumatic tourniquet
Lee et al. (2017) [15]	3000	MP	Hb < 80 g/L	N/A	Primary TKA	General anesthesia	Doppler ultrasonography	Yes
Yuan et al. (2017) [14]	N/A	MP	Hb < 80 g/L or anemia symptoms	10 mg/day rivaroxaban	Primary TKA	General anesthesia	Doppler ultrasonography and chest computed tomography	Yes
Perreault et al. (2017) [13]	3900	N/A	Hb < 80 g/L or anemia symptoms	N/A	Primary TKA	N/A	N/A	N/A
Zohar et al. (2004) [21]	3000	N/A	Hematocrit < 28%	40 mg/day enoxaparin	Primary TKA	N/A	Doppler ultrasound imaging and signs of lower limb DVT(swelling or increase in calf diameter)	Yes
Alipour et al. (2013) [22]	3000	N/A	N/A	40 mg/day enoxaparin	Primary TKA	Standard general anesthesia	N/A	Yes
Bradshaw et al. (2012) [20]	6000	MP	Hb < 70 g/L or anemia symptoms	40 mg/day enoxaparin	Primary TKA	N/A	N/A	Yes

TXA tranexamic acid, N/A not applicable, Hb hemoglobin, MP medial parapatellar approach, DVT deep vein thrombosis, TKA total knee arthroplasty

ISSN: 1749-799X